Ticlopidine, trials, and "torture".
نویسندگان
چکیده
منابع مشابه
Ticlopidine, trials, and torture.
Clinical trials of stroke prevention in patients at high risk are based on, at best, a few hundred outcome events. Therefore, the conclusions of single trials are necessarily subject to random error. The Ticlopidine Aspirin Stroke Study (TASS) trial, which directly compared ticlopidine with aspirin, is no exception: the 3-year event rate for stroke or death (all causes) was 17% for ticlopidine ...
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The thienopyridines ticlopidine and clopidogrel are inhibitors of platelet function in vivo. Their mode of action has not been defined, but it appears that they require conversion to as yet unidentified metabolites that are noncompetitive antagonists of the platelet ADP receptor. Inhibition of platelet aggregation with these compounds is delayed until 24 to 48 hours after administration. Maximu...
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Ticlopidine, Trials, and "Torture" To the Editor: The title of the editorial by van Gijn and Algra, "Ticlopidine, Trials, and Torture," may leave the impression that real torture is a phenomenon of the distant, cruel past, and that the word "torture" can now be used to describe any misconduct towards persons or, as in this case, scientific data. Torture, however, is a sad and unacceptable reali...
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This paper discusses the psychosexual correlations and psychological consequences related to torture and behavioral acts that are fundamentally torturous. The influence of participation by learning and the relationship of acts to thought and thought to acts are further discussed to raise awareness to the effects of torture on the torturer. Theories from multiple disciplines are presented in an ...
متن کاملContributory torture.
Sir, Contributory torture occurs when the behavior of the offender influences the behavior of the interrogator or, in a broader sense, anyone disciplining the offender. The word contributory is used because if the offender acts up, he/she is part of the reason for the type of punishment he/she receives. For example, if two people are arrested and one follows the directions of the officer and th...
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ژورنال
عنوان ژورنال: Stroke
سال: 1994
ISSN: 0039-2499,1524-4628
DOI: 10.1161/str.25.12.2503b